PRP Vs. PRF: Know The Difference In Medical Spa Treatments

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Are you confused about the difference between PRP (platelet-rich plasma) and PRF (platelet-rich fibrin) treatments in medical spas? Below, we will clarify the distinctions between these two innovative procedures and help you understand how they work and how they can benefit you.


At Senara Health and Healing Center & Spa in Peoria, we prioritize providing our patients with the most comfortable and effective treatments. That’s why we use PRF for skin rejuvenation and scar treatment, as it offers a more comfortable experience, better results, and does not require an anticoagulant. Contact us today to learn more about our medical spa PRF treatments and schedule a consultation with our experienced team.

PRP and PRF: What Are These Medical Spa Treatments?

In the field of medical spa treatments, it can be challenging to grasp the nuances and distinctions between various procedures. Stem cell therapy, platelet-rich plasma (PRP) treatment, and platelet-rich fibrin (PRF) treatment all offer potential benefits, but it’s crucial to understand how they are created, how they function, and their differences.
Keep reading as we delve into the main similarities and variations between PRP and PRF treatments, providing you with valuable insights to make an informed decision. If you’re intrigued by any of these treatments, don’t hesitate to contact Senara Health and Healing Center & Spa in Peoria for a consultation.

Obtaining the Blood Sample

To obtain either PRP or PRF, a blood sample must be taken from the patient. To create the serum from the sample, it must run through a centrifuge to separate different parts of the blood.

  • PRP: The blood sample needed to create a PRP serum is greater than the sample required for a PRF serum. The centrifuge also runs at different speeds to create the two different serums. To create PRP, the centrifuge spins at a higher speed to separate the heavier white blood cells and stem cells from the lighter platelets and plasma.
  • PRF: The makeup of a PRF serum is slightly different because the centrifuge runs slower and does not fully separate the heavy blood cells from the platelets.
    Revitalize Your Skin with PRF Serums for Cell Rejuvenation

PRF serums, created with a combination of white blood cells and stem cells, could help enhance the effectiveness of cell rejuvenation treatments. By utilizing a lower centrifuge speed, PRF treatments may reduce trauma to blood cells, resulting in a serum that potentially retains more white blood cells and stem cells than PRP serums. Experience the benefits of PRF serums for revitalizing your skin at select medical spas. Consult with experts to find out if PRF treatments are right for you.

Differentiating Blood Separation in PRP and PRF Treatments

  • PRP: At high speeds, the centrifuge can separate the blood into two distinct layers to create PRP. At the bottom of the test tubes are white blood cells and stem cells. These will not be injected into the patient. Instead, the lighter layer that sits on top — which includes the growth factors and proteins — is what’s drawn from the sample and injected into the patient.
  • PRF: When the centrifuge spins at a lower speed, it cannot separate the different factors of the blood sample entirely. This, along with less trauma being inflicted on the cells, is what allows more white blood cells and stem cells to remain in the platelet layer that creates the PRF serum.

Platelet Count

  • PRP: Serums with PRP are effective because of the higher concentration of platelets than the body. A sample of PRP generally has two to five times more platelets than what is found in the body.
  • PRF: On the other hand, PRF has up to 10 times more platelets than the body. This is great news for medical spas because a higher concentration of platelets is more effective for skin rejuvenation.

PRP and PRF: Which One Is Better?

While PRP and PRF treatments show incredible potential for revitalizing skin, PRF is clearly an improvement in the process as a whole. For the patient, the procedure is more comfortable because it requires a smaller sample of blood. The treatment is more effective because the centrifuge doesn’t spin as quickly, retaining more healthy white blood cells and stem cells to increase healing.
Not only that, but a PRF serum doesn’t require an anticoagulant added to the solution to prevent it from becoming too clotted. While PRP requires this anticoagulant, PRF does not because the mixture creates a spongy fibrin matrix that doesn’t clot. This makes the solution that much more natural than PRP.

PRP Vs. PRF Medical Spa Treatments

PRP vs. PRF Medical Spa Treatments at Senara

At Senara Health and Healing Center & Spa in Peoria, we are constantly working to improve our medical spa treatments. This is why we use PRF for skin rejuvenation and scar treatment. We believe it creates a more comfortable experience as well as better results for our patients. Contact us today to request an appointment if you’re interested in a medical spa PRF treatment.

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