With advancements in medical spa treatments, it can be difficult to wrap your head around how different treatments work. There’s stem cell therapy, platelet-rich plasma treatment, and platelet-rich fibrin treatment — but what’s the difference?

We’ve talked about how stem cells are the building blocks of all other cells, capable of helping repair and regenerate damaged tissue. PRP and PRF are similar, but it’s important to understand how they’re created, how they work, and the differences between the two. 

In today’s blog, we are going to explore the main similarities and differences between these two types of treatments available in medical spas. If you’re interested in one of our treatments, contact Senara Health And Healing Center & Spa in Peoria to schedule a consultation.

The Blood Sample

In order to obtain either PRP or PRF, a blood sample must be taken from the patient. To create the serum from the sample, it must run through a centrifuge to separate different parts of the blood.

The blood sample needed to create a PRP serum is greater than the sample required for a PRF serum, though. The centrifuge also runs at different speeds to create the two different serums. To create PRP, the centrifuge spins at a higher speed to separate the heavier white blood cells and stem cells from the lighter platelets and plasma. 

The makeup of a PRF serum is a little different though, because the centrifuge runs at a slower speed and does not fully separate the heavy blood cells from the platelets. 

The Separation Process

New research has shown that a serum that contains some white blood cells and stem cells is more effective than those without. For this reason, many medical spas that offer these types of treatments are beginning to create PRF serums to help with cell rejuvenation rather than just PRP.

Along with a greater number of healing factors within a PRF serum, the lower speed that the centrifuge spins at causes less trauma to the individual blood cells overall. This allows the process to retain more white blood cells and stem cells to be included in the PRF serum than the PRP serum.

What They Contain

At high speeds, the centrifuge is able to separate the blood into two distinct layers to create PRP. At the bottom of the test tubes are white blood cells and stem cells. These will not be injected into the patient. Instead, the lighter layer that sits on top — which includes the growth factors and proteins — is what’s drawn from the sample and injected into the patient.

When the centrifuge spins at a lower speed, it is unable to separate the different factors of the blood sample entirely. This, along with less trauma being inflicted on the cells, is what allows more white blood cells and stem cells to remain in the platelet layer that creates the PRF serum.

Platelet Count

PRP serums are effective because of the higher concentration of platelets compared to that of the body. A sample of PRP generally has two to five times more platelets than what is found in the body.

PRF, on the other hand, has up to 10 times more platelets than the body. This is great news for medical spas because a higher concentration of platelets is more effective for skin rejuvenation.

Which One Is Better?

While PRP and PRF treatments show incredible potential for revitalizing skin, PRF is clearly an improvement upon the process as a whole. For the patient, the procedure is more comfortable because it requires a smaller sample of blood. The treatment is more effective because the centrifuge doesn’t spin as quickly, retaining a higher number of healthy white blood cells and stem cells to increase healing.

Not only that, but a PRF serum doesn’t require an anticoagulant added to the solution to prevent it from becoming too clotted. While PRP requires this anticoagulant, PRF does not because the mixture creates a spongy fibrin matrix that doesn’t clot. This makes the solution that much more natural than PRP.

Treatments At Senara

At Senara Health And Healing Center & Spa in Peoria, we are constantly working to improve our medical spa treatments. This is why we use PRF for skin rejuvenation and scar treatment. We believe it creates a more comfortable experience as well as better results for our patients. Contact us today if you’re interested in a medical spa PRF treatment.